A phase I trial of IMGN779 enrolled 50 adult patients with relapsed or refractory AML, and the most common toxicities included febrile neutropenia, nausea, diarrhea, and fatigue

A phase I trial of IMGN779 enrolled 50 adult patients with relapsed or refractory AML, and the most common toxicities included febrile neutropenia, nausea, diarrhea,…

HUVECs were treated with different antagonists: 10 M U0126 (MEK/ERK1/2), 10 M LY294002 (PI3K), 100 M 5-HD (mitoKATP), and 10 M L-NAME (NOS)

HUVECs were treated with different antagonists: 10 M U0126 (MEK/ERK1/2), 10 M LY294002 (PI3K), 100 M 5-HD (mitoKATP), and 10 M L-NAME (NOS). ATP-induced defensive…

In boosts using pam-peptide (which require crosspresentation by Compact disc8a+ DCs) CTL expansion also necessary MDA5 stimulation and was mediated via IL15 but could happen in the lack of IFN-I alerts

In boosts using pam-peptide (which require crosspresentation by Compact disc8a+ DCs) CTL expansion also necessary MDA5 stimulation and was mediated via IL15 but could happen…

Supplementary MaterialsPresentation_1

Supplementary MaterialsPresentation_1. confirm these encouraging observations inside a setting closer to medical challenges and to deeply characterize the next-generation TCPs. Using cytomegalovirus (CMV) as model,…

Data Availability StatementThe data that support the results of this study are available from Eli Lilly and Company but restrictions apply to the availability of these data

Data Availability StatementThe data that support the results of this study are available from Eli Lilly and Company but restrictions apply to the availability of…